Essay Sample on Proteomics What is the Interest for Researchers

Essay Sample on Proteomics What is the Interest for Researchers Proteins are a basic building block of life on earth. They are the molecules that provide structure, produce energy, and allow communication, movement and reproduction within a cell. They, along with carbohydrates, amino acids, and phospholipids, are the key macromolecules that make up organisms. The body of proteins that make up an organism is referred to as its proteome. Proteomics is the study of these proteomes, including the identification of the proteins and their physiological functions. The study of proteomics had declined in recent years, but the inception of the Human Genome Project ten years ago revived interest for many researchers. Since then, the proteomes of numerous organisms have been determined. The Human Genome Project determined that the human body contains 30,000 genes. This translates to anywhere from 300,000 to one million possible proteins. The importance of proteomics largely lies in drug design and synthesis. Hopefully, new disease markers and drug targets can be identified that will help design products to prevent, diagnose and treat disease. This cannot be accomplished without knowledge of the proteome, however. A protein is a biological polymer that usually consists of hundreds of amino acid monomers. The general structure of an amino acid is a carbon atom to which four functional groups are bonded. Three of the groups include a hydrogen atom, an amine group, and a carboxylic acid group. The fourth group, or ‘R’ group, is a hydrocarbon chain. This R group is unique to each particular amino acid and is what determines one amino acid from another. The primary structure of a protein is its linear sequence of amino acids bound by peptide bonds between a nitrogen atom of one monomer and a carbon atom of another. Disulfide bonds between cysteine residues within the molecule stabilize it. This structure determines the secondary, tertiary, and quaternary structures of the protein as well. Proteins are highly specialized, and a single change in an amino acid monomer can result in a completely different function, or no function at all for the protein. Thus, the primary structure is of utmost importance. The secondary structure of proteins consists of the primary structure formed into two possible regular structures. These are an alpha helix or a pleated sheet. These structures can organize themselves in a repeating fashion or randomly. Disulfide bonds determine the secondary structure, while hydrogen bonding also stabilizes the conformation. A protein’s tertiary structure is the overall 3-D configuration of the complete protein. Amino acid residues that are far apart in a primary structure can have steric relationships in 3-D form, and the tertiary structure considers this. The tertiary structure is the most thermodynamically stable for the protein in a certain environment; it can change with environmental changes. This is how proteins are denatured. A protein may consist of several subunits. The quaternary structure of a protein is made up of all of these subunits bound together by electrostatic and hydrogen bonds. Multisubunit proteins are called oligomers and all of the component parts are monomers or subunits. Proteins may also contain non-amino acid functional structures such as a lipid or a carbohydrate. In order for proteins to be studied, they must first be isolated. In one dimension, the proteins are separated by charge based on their isoelectric points. The migration of different proteins in an electrically charged environment of graduated pH can separate them when their isoelectric points are different. The proteins move toward the pH at which they have no net charge. The main way this has been achieved is through 2-D polyacrylamide gel electrophoresis, or 2-D PAGE. This experiment can achieve the separation of several thousand different proteins in one gel, while high resolution 2-D PAGE can resolve up to 10,000 proteins per gel. Coomassie blue, silver, and SYPRO Ruby Red stains are typically used to visualize the proteins’ migrations. Mass spectrometry is a technique used for the determination of the mass of a compound; however, it is also useful in protein identification. The spectrometer ionizes the protein, and this charged molecule is sent into an analyzer on the basis of charge repulsion. This analyzer resolves the proteins based on their mass to charge ratio, thus separating them. The detector passes the information to the computer for analysis and identification. Fragmentation can cause problems in protein separation, so ionization methods that minimize formation of fragments are most useful. These methods include matrix-assisted laser desorption/ ionization, or MALDI and electrospray ionization, or ESI. Once a protein has been isolated, its structure must be determined. Secondary and tertiary protein structures can be found by two methods: X-ray crystallography and nuclear magnetic resonance. Both methods require that the protein be better than 95% pure for the best results, so the isolation methods are extremely important. The experimental technique can include gel or column separation, dialysis, differential centrifugation, salting out, or HPLC. The choice and order of experiments is modified to suit the protein of interest. In order to study a protein’s structure through X-ray crystallography, it must be crystallized. The most common methods of crystallization are batch methods and vapor diffusion. A supersaturated solution is formed which causes the protein to associate with other protein molecules. The formation of this solution often requires the addition of precipitants such as polyethylene glycol or certain salts. The identification of the amino acids in the protein are again important here, since they can determine the exact reagents and chemical and physical conditions used to crystallize the protein. The crystals are then mouted and snap frozen. This is accomplished by exposing them to cryogenic liquid or gas. In X-ray crystallography, the crystals are subjected to X-rays containing a heavy metal atom. This method can determine the protein’s secondary and tertiary structure. The X-rays are scattered by the crystal in a pattern unique to the protein. One drawback is that the radiation can damage or backscatter; keeping the crystals supercooled minimizes this side effect and allows the crystals to be stored and reused. A model of the protein is then constructed using the data translated into electron density maps. This method is highly important in drug design, since it is very precise and can reveal crucial structural data. Nuclear magnetic resonance, or NMR, spectroscopy involves the alignment of nuclear dipoles of a sample in a magnetic field. These dipoles can change orientation back and forth in a magnetic field and absorb and emit energy for each turn. The spectrometer contains an antenna within the magnet; radio waves are pulsed by this antenna through the magnet. The sample absorbs these pulses as energy and then emits them sometime later. This time is measured and stored on the computer. Most often, pulse sequences are used that take advantage of the strong nuclear dipole of the hydrogen nucleus. The information gained from this experiment allows researchers to map the chemical bond connectivity and the spatial orientation of the proteins. This method is particularly useful in determining the function of active sites on enzymes. NMR spectroscopy has several advantages over X-ray crystallography. One is that NMR requires no crystallization in order for the protein’s structure to be studied. Currently, this method can resolve proteins with molecular weights up to 30,000 Daltons; it is predicted that structures with molecular weights of up to 100,000 Daltons can soon be determined through this method in the coming years. Another advantage is that NMR is sensitive to motions on the millisecond to second range, which can be directly studied. Even motions as small as those of the nanosecond to microsecond scale can be studied indirectly. X-ray crystallography is also an extremely time-consuming process, and the crystalline structures can be difficult to maintain. However, the greatest advantage of NMR over X-ray crystallography is NMR’s ability to reveal the details of specific structural sites without solving the entire structure. Current studies in proteomics include the research being done by biochemists at the University of Washington in Seattle. These scientists are studying environmental effects on the transcription and translation of the mRNA molecule. This is the nucleic acid that codes for the manufacture of proteins within the cell. In an earlier study, they reported the use of Translational State Array Analysis, or TSAA. This method allowed for the simultaneous study of mRNA level and translation. They chose Saccharomyces cereviciae as their model and arrested it with the temperature-sensitive cdc 15-2 allele. A control was run in which forty-eight mRNA molecules changed upon release from arrest. However, when the temperature of the cdc 15-2 allele was lowered from 37 C to 25 C, fifty-four molecules of mRNA were affected. Therefore, regulating the translational level seems to affect directly the response of yeast cells to external cues. Another study done recently again involves the use of Saccharomyces cereviciae. This study, completed at Johns-Hopkins University, attempted to investigate whether indexing a proteome according to its C-terminal sequences could be of use in functional classification of proteins. The basis for this experiment is that the protein C-termini are capable of being recognition signatures for many biochemical processes. The extent to which carboxyl terminal sequences are conserved within the proteome is unknown, but this may be related to certain biological functions and therefore has great importance. The researchers analyzed the terminal sequences of Saccharomyces cereviciae and found that known and unknown terminal sequences existed. This result supports that there may be additional carboxyl terminal signals whose biological functions are not yet known. You can order a custom essay, term paper, research paper, thesis or dissertation on Proteomics topics at our professional custom essay writing service which provides students with custom papers written by highly qualified academic writers. High quality and no plagiarism guarantee! Get professional essay writing help at an affordable cost.

Learn how to get only As for your paper!

Learn how to get only As for your paper! How to End Failing Grades in Paper Writing Failing grades on papers in college is a GPA â€Å"killer.† When a major research paper can be fully one-third of a course grade, it is easy to understand that no one ever wants a â€Å"D† or â€Å"F† on one of them. And yet those grades are quite common, when students submit writing paper assignments that are just not up to the standards that college-level work demands. If you are the recipient of some of these kinds of grades, you know you have to something to fix the issues you have. But you can’t fix those issues unless you first identify them. So, here are common causes of poor writing grades, and if you can identify yours, you’ve made the first step toward grade recovery. Course overload: Some students are just too ambitious and enroll in either too many courses or in too many really challenging courses. And many students have part-time jobs that they must keep due to their financial situations. Take a long hard look at the courses you are currently in. If it is early in the semester, you might want to consider dropping ones in which you are struggling and picking up a â€Å"fluff† course to keep your credit load the same. This will naturally give you more time to spend on the essay and paper writing for the remaining courses. Time Management/Procrastination: If you are not organizing your time efficiently, you will always end up trying to get those essays and papers completed at the last minute. This is a â€Å"death knell,† because you will never do a good job when rushed. And if you are the type of person who is continually putting things off and choosing social time instead, you will always have your â€Å"back up against the wall† when you finally do have to get a paper in. Students who get consistently good grades on writing assignments schedule time for them in advance and stick to a schedule of daily assignments, time for work on longer-term essays and papers, down-time to just chill, job, and other co-curricular and social activities. If you manage yourself well, you will have time for all of these things. Lack of Motivation: If you are forced to take a course in which you have no interest, do not feel alone. Every college student faces this issue, and it is really hard to get motivated to write an essay or a paper on a topic you really dis-like. There is no cure for this, but you will have to force yourself to put together a credible piece of writing anyway. One thing you can do is get online and read sample essays and/or papers on the topic, and these will give you some good ideas for development and perhaps some current resource materials that you can use. A word of caution: all of your professors have plagairism-detection software at their disposal, and, in fact, a number of colleges now require that a student submit a TurnItIn report with their essays and papers. Don’t try to â€Å"game the system!† Organizing Information/Data from Several Sources: Writing a paper that will earn a good grade means that information and data is presented in an organized fashion. When several sources are used, synthesizing that content can be a challenge, especially when you have to be very careful about the specific source of each piece. If you struggle with combining the results of research into logical sub-topics, you need an organizing system. In high school, you probably used note cards, and that works for many students. If it doesn’t work for you, try listing each sub-topic at the top of a page and then enter information that pertains to that sub-topic (with the source and page number of course) all on two or three pages. You can then print those page out, lay them before you, and have a complete picture of the information you have on a sub-topic. Combining similar pieces of data from different sources is then an easy task. English writing skills: If you do not have proficient composition skills, you probably already know it. Even though a paper may be for a history class, lack of good writing automatically lowers a grade. Professors are, after all, human, and they get frustrated when they have to read anything that is poorly written – they cannot focus on your content, no matter how good it is. You must get help if this is your issue, and here are your options: First, commit to remediating your skills through an online course or a tutor. This will take time but eventually pays off. Make use of the writing lab on your campus – it’s free, and there are good writers there to help you. Write your rough draft and have a friend who is a good writer review and edit it for you. Get a writing style app that will find your major errors and give you solution suggestions. Contact a custom paper writing company and get original custom writing of your essays and papers. The additional â€Å"plus† of this option is that you can study the pieces as you work to improve your own skills.

Health Leadership and Management Essay Example | Topics and Well Written Essays - 3500 words

Health Leadership and Management - Essay Example From the report it is clear that the management concepts of leadership and identification and establishment of a risk management process are to be applied for the ultimate design of a health care process. Such processes are more required at the Intensive Care Unit (ICU)/facilities of any hospital as ICU is one of the most critical services of any hospital and the quality of patients' response is important in determining the success of the entire hospital itself. As the essay highlights low evidence based practices are cleaning insertion site, use of heparin,tunneling,routine catheter change, routine Ab prophylaxis, hand washing compliance and use of Sucralfate; medium level evidence based practices are peri-operative normothermia, continuous oscillation,suprapubic catheters, barrier Precautions and Ab restrictions; high evidence based practices include supplemental perioperative oxygen, semi-recumbent position ,selective decontam- GI tract and silver alloy-coated catheters, to quote a few. While these best practices are indicative of the desirable course of actions in ICU situations ;they perhaps indicate more to the risk perceptions and associated risk bearing events within the ICU environment. There are noticeable gaps in prescription of these best practices and their actual practices which leads to occurrence of adverse events in ICU care. A careful identification and documentation of deviations which have resulted in adverse incidents is the much needed innovation for ICU management.

Franchising & Small Case Study Analysis Essay Example | Topics and Well Written Essays - 1250 words

Franchising & Small Case Study Analysis - Essay Example In addition, the nature of the business assures customers of different income backgrounds. In this sense, it is possible to have daily substantial sales (Lundahl, 2012). The business has two modes of serving customers. This pertains to internal partaking of food and delivery services. In most instances, customers partake of already prepared fries and artificial juice products. It is vital to note that preparation of natural juices might take different dimensions as concerns the taste and preference of customers. The institutions and businesses provide a significant market to Bucking Bull’s products as the outlet delivers food and drinks to the same. There are two types of delivery services. They are either on short or long term delivery terms. Short term delivery plans depend on daily orders. On the other hand, the business might deliver larger quantities of foods on monthly agreements and contracts with businesses. It is vital to stress that there is substantial competition in Bucking’s venue of conducting business. This relates to the mushrooming of smaller food outlets. The chance for expansion, in the industry, places Bucking at a vulnerable position for succumbing to competitive pressure (Andrews, 2007). This is because new businesses are tactful at satisfying loopholes of existing businesses. However, this is mitigated by creating a customer loyalty of following their recommendations for improvement of business. The first innovation pertains to value addition services and development of a brand that customers would associate with the same. It is vital to note that food outlets usually study the recipes of the best restaurant. In this sense, they would normally make similar foods across a chain of different outlets. Therefore, a brand name establishes a competitive edge that improvement in food services would not accomplish. A brand name is vital in pushing up revenues as more customers are

Why Intelligent People Fail Essay Example for Free

Why Intelligent People Fail Essay 1. Lack of motivation. A talent is irrelevant if a person is not motivated to use it. Motivation may be external (for example, social approval) or internal (satisfaction from a job well-done, for instance). External sources tend to be transient, while internal sources tend to produce more consistent performance. 2. Lack of impulse control. Habitual impulsiveness gets in the way of optimal performance. Some people do not bring their full intellectual resources to bear on a problem but go with the first solution that pops into their heads. 3. Lack of perserverance and perseveration. Some people give up too easily, while others are unable to stop even when the quest will clearly be fruitless. 4. Using the wrong abilities. People may not be using the right abilities for the tasks in which they are engaged. 5. Inability to translate thought into action. Some people seem buried in thought. They have good ideas but rarely seem able to do anything about them. 6. Lack of product orientation. Some people seem more concerned about the process than the result of activity. 7. Inability to complete tasks. For some people nothing ever draws to a close. Perhaps it’s fear of what they would do next or fear of becoming hopelessly enmeshed in detail. 8. Failure to initiate. Still others are unwilling or unable to initiate a project. It may be indecision or fear of commitment. 9. Fear of failure. People may not reach peak performance because they avoid the really important challenges in life. 10. Procrastination. Some people are unable to act without pressure. They may also look for little things to do in order to put off the big ones. 11. Misattribution of blame. Some people always blame themselves for even the slightest mishap. Some always blame others. 12. Excessive self-pity. Some people spend more time feeling sorry for themselves than expending the effort necessary to overcome the problem. 13. Excessive dependency. Some people expect others to do for them what they ought to be doing themselves. 14. Wallowing in personal difficulties. Some people let their personal difficulties interfere grossly with their work. During the course of life, one can expect some real joys and some real sorrows. Maintaining a proper perspective is often difficult. 15. Distractibility and lack of concentration. Even some very intelligent people have very short attention spans. 16. Spreading oneself too think or too thick. Undertaking too many activities may result in none being completed on time. Undertaking too few can also result in missed opportunities and reduced levels of accomplishment. 17. Inability to delay gratification. Some people reward themselves and are rewarded by others for finishing small tasks, while avoiding bigger tasks that would earn them larger rewards. 18. Inability to see the forest for the trees. Some people become obsessed with details and are either unwilling or unable to see or deal with the larger picture in the projects they undertake. 19. Lack of balance between critical, analytical thinking and creative, synthetic thinking. It is important for people to learn what kind of thinking is expected of them in each situation. 20. Too little or too much self-confidence. Lack of self-confidence can gnaw away at a person’s ability to get things done and become a self-fulfilling prophecy. Conversely, individuals with too much self-confidence may not know when to admit they are wrong or in need of self-improvement.

New Learning Strategies for Generation X Essay -- Education Careers Es

New Learning Strategies for Generation X Generation X workers resent the labels that have been used to describe them: slackers, arrogant, disloyal, having short attention spans. In fact, these descriptions are less likely to reflect the behaviors of individuals in Generation X than the perceptions of managers who are not attuned to new ways of learning. This Digest investigates ways in which the learning characteristics of the young adults classified as Generation X reflect the need for the new teaching and learning strategies promoted by cognitive scientists, such as learning in context, cooperative learning, and real-world application of knowledge. The Life Experience Gap The gap between Generation X and earlier generations represents much more than age and technological differences. It reflects the effects of a changing society on a generation. Young adults born between 1961 and 1981 have radically different life experiences than those in generations before them. In their youth, many Generation Xers were "latchkey kids"--children who saw both of their parents working and/or furthering their education. Many of them were raised in single parent homes, the children of divorced parents. They grew up with "fast" food; "remote control" entertainment; and "quick response" devices such as automatic teller machines and microwave ovens, all of which provided instant gratification. As young adults, Generation Xers find themselves facing limited economic prospects and a society different from any preceeding them. The previous generation saw rapid economic growth and expanding opportunities. Generation Xers see corporate downsizing and layoffs, limited opportunities for career positions, and an economically troubled socie... ..., p. 1. <http://www.physics.wisc.edu/~shalizi/Generation-x_Articles/brinkley/> Caudron, S. "Can Generation Xers be Trained?" Training and Development 51, no. 3 (March 1997): 20-24. Hornblower, M. "Great Xpectations." Time 129, no. 23 (June 9, 1997): 58-68. Losyk, B. "How to Manage an Xer." Current 392 (May 1997): 12 Newmann, F. M. et al. "Authentic Pedagogy: Standards that Boost Student Performance." Issues in Restructuring Schools. Issues Report No. 8. Madison, WI: Center on Organization and Restructuring of Schools, 1995. (ED 390 906) Sachs, P. Generation X Goes to College. An Eye-Opening Account of Teaching in Post- modern America. Chicago, IL: Open Court Publishing Company, 1996. Wagschal, K. "I Became Clueless Teaching the GenXers." Adult Learning 8, no. 4 (March 1997): 21-25. "Your Life." USA Today 125, no. 2622 (March 1997): 6.

Inta Omri by Oum Kalsoum Essay

Enta Omri is Egyptian singer and songwriter Oum Kalsoum’s best known work. The song Enta Omri has been revived and reinterpreted many times over the past few decades. Even then, no one can compare to the original recordings of Oum Kalsoum, who was the best singer to come from the Middle East. Many contemporary Western artists and musicians have been significantly influenced by her work. Famous artist known to be admirers of her body of work range from such stars as painter Salvador Dali to rock star Bono. Today, her popularity has not faded and the recordings of her songs continue to sell very well in the Middle East, with about one million records sold each year. The song Enta Omri has significantly influenced Oum Kalsoum as an artist. The lyrics of her subsequent songs followed the theme of Enta Omri, centered on the topics of love, longing for someone, or the loss of a loved one, much like the topics prevalent on country music today. Her musical performances are also very long by today’s standards. While the official recording of the song Enta Omri is about an hour, her live performances could last for several hours. The people listening to her songs are mesmerized by Oum Kalsoum’s vocal range, who had one of the deepest singing voice for females. References: 1. Shira. Inte Omri: You Are My Life. Retreived on November 28, 2008. 2. You Tube. Omm Kalthoum-Inta Omri.Retreived on November 28, 2008. 3. Imeem. Inta Omri by Yahel. Retreived on November 28, 2008. 4. Egypt State Information Service. Umm Kolthoum. Retreived on November 28, 2008. 5. Al-Ahram Weekly. The Voice of Authority. Retreived on November 28, 2008. 6. Al-Ahram. Umm Kuthoum Superstar. Retreived on November 28, 2008. 7. OumKalthoum. org. Oum Kalthoum. Retreived on November 28, 2008. 8. Al-Masriq. Umm Kulthum. Retreived on November 28, 2008.

How was Islam founded? Essay

Islam was founded in the 17th century when the angel Gabriel revealed to the prophet Muhammad the revelations of God. What is the difference between a Shi’ite Muslim and a Sunni Muslim? The Sunni believes that the legitimate leaders to be recognized by the Muslims are Mohammad’s successors – the four caliphs. On the other hand, the Shi’ites believe that only the heirs of the fourth caliphs should succeed as a religious leader. Why was the site of the Great Mosque of Cordoba so appropriate? The Great Mosque is appropriate because it was originally built as a church and later became a mosque for the Muslims, which expanded and became the second-largest mosque. What events led to the end of the Muslim world in 1492? The main event that marked the end of the Muslim world in Iberia was the conquest of Granada. On the second day of January 1492, the Muslim leader of Granada gave up his kingdom to the Catholic Monarchs. This became the end of the reconquistas when all of the peninsulas were recaptured by the Catholics. How was the Ottoman Empire formed? The formal Ottoman Empire rose during the year 1299-1453, which is associated with the fall of the Roman Empire. Under this government, the religious and ethnic minorities had freedom from the central control with regards to their internal issues or concerns. How does the life of Galla Placida bring the fall of the Roman Empire to life? During the animosities between the Goths and the Emperor, Placidia was captured and later on married Athaulf after the fall of Rome and they settled in Southern France. How did the Norse use animal style in their art? With the use of seminaturalistic lions and bird motifs, the Norse used animal style in their art to create pieces that will represent the 9th to 12th century. Why were manuscript covers often reused or stolen?   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Manuscript covers were often reused or stolen because it is made of silver and gold. What beautiful artistic elements characterize the Book of Kells? The manuscripts were made interesting by the use of vibrant colors and intricate knotwork of human and animal figures. The decorations were filled with Christian symbolism that illuminates the major theme of the illustrations. What was the fate of most Ottonian architecture and why? It is a pre-Romanesque style of architecture and also known as the Ottonian Renaissance. Architecture was influenced by Carolingian tradition. Of the vast number of Churches built, only a few are well-reserved, most have disappeared.

To Kill a Mockingbird3 essays

To Kill a Mockingbird3 essays Title of work: To Kill A Mockingbird In 1960 Harper Lees To Kill A Mockingbird was first published. Interviewers were stunned when they first met Harper Lee, after reading this novel. They often felt as if they were coming face to face with a grownup version of Scout Finch, the six-year old of the novel. Her features at thirty-five marked her as a former tomboy. Harper Lee was born in 1926, she would have been the same age as Scout during the time this story took place. She grew up in Monroeville, Alabama, a place much like the town of Maycomb described in this novel. Harper Lees father, Amasa C. Lee was a small town lawyer with an unusual first name. Just like Atticus Finch in this novel. Harper Lee attended the University of Alabama and spent a year in England as an exchange student at Oxford University. In 1950, she quit law school and moved to New York, and starting her dream career devoting her time to writing. Much of the background information for the novel came from Lees childhood experiences; the plot was mostly all from her imagination. In 1957, she finally finished the rough draft for To Kill A Mockingbird. The first editor turned it down; she spent much of two and a half more years reworking it. Finally in 1960, To Kill A Mockingbird was ready for publication. This book was a real success with readers young and old as well as the reviewers. The movie rights were sold immediately. In 1961, Lees success was crowned with a Pulitzer Prize for fiction, making her the first woman to win the award since 1942. Harper Lee has a very unique style in this novel. He uses different types of writing to get your attention and help you picture a mental image. Lee uses imagery throughout this novel. As soon as you start reading she has already sketched out the town scenery and a description of Boo Radley. Everything that happens takes on a clear focus with the way she uses imagery. The style that Lee...

Whats in store for the workplace in 2018ÂÂ

Whats in store for the workplace in 2018   As one year ends and another begins, it’s a good time to start thinking about what may be lying ahead for you work-wise in 2018. It’s obvious that the world is changing pretty rapidly, with advances in technology and consumer demands having a tremendous impact on the workplace across all industries. Here’s an example- it’s fair to say that the traditional routine of commuting to work Monday through Friday and punching a clock from 9 a.m. to 5 p.m. is disappearing; in many professional sectors it has already gone the way of the dinosaur and in others it’s quickly evaporating, leaving many of us to wonder what’s next. A recent article on Ladders made some interesting predictions regarding workplace changes that could possibly be in store for us in 2018. If you’re wondering about what might be lying ahead for you at your current job or if the coming year might be a good time to make a career change, then keep reading!More flexible work ar rangementsIf there’s one thing that technological advances in recent years have changed it’s the ability to work from absolutely anywhere- these days, you can even get work done while waiting on line at the grocery store. More people are being more productive than ever before on their laptops, tablets, and smartphones and getting work done at home, while running errands or waiting for appointments, or wherever else they have pockets of spare time (and Internet access).Progressive employers have already capitalized on this trend by allowing their employees to take advantage of opportunities to work remotely. This can be a real win-win situation- employees get to save on the time, hassle, and expense of having to commute back and forth from work every day, and employers get to save money on things like office supplies and have a happier staff (and potentially greater employee retention from the added perk). Count on this telecommuting trend to continue through 2018 and b eyond.Decreasing full-time positionsModern innovations in the workplace have ushered in a new way of thinking about employee productivity. Simply put, companies are discovering creative ways to do more with less and to leverage new technology to empower fewer employees to get more work done. As a result, companies are reimagining what they need from a dedicated staff and are shifting away from hiring full-time employees and towards hiring part-time, freelance, and contract employees as needed for work projects- for better or for worse. This represents a real cost-savings for the average company, and in an economy in which domestic growth is sluggish at best, it’s a compelling option that less and less companies will shy away from in 2018.The rise of employee engagementAs companies learn to do more with less and rely on a smaller, more valuable core group of employees to drive productivity, expect to see a greater focus on making sure that these employees are fully engaged and happy. Why is this a growing trend? Employee turnover with leaner staffs can represent a significant loss of time, money, and institutional knowledge, so doing whatever it takes to keep folks happy- and in place- will become more strategically important. This can take lots of different forms- from added incentives and perks on the job to more flexibility regarding work-life balance and life outside of work.Greater cultural diversity and awarenessIt’s obvious that most progressive societies are moving towards a greater understanding, awareness, and appreciation of cultural diversity, and this is trickling down into the modern workplace. In 2018, expect to see most companies enhancing their efforts to ensure that their workplaces reflect the rich diversity that exists in our increasingly globalized world. Furthermore, according to Amy Cooper Hakim, Ph.D. and industrial-organizational psychologist, â€Å"more companies will hold training classes (both virtually and in-person) to ensure that all members of an organization treat others with respect. This respect is vital for interactions with employees, employers, stakeholders, and clients.†There you have it- some workplace predictions for the coming year. Although you can expect to see some variation across industries and companies, you can count on these trends continuing in the workplace in general through 2018 and beyond.

Chapter 10 & 11 Assignment Example | Topics and Well Written Essays - 500 words

Chapter 10 & 11 - Assignment Example nizations safety, they supervise and monitor to ensure that all the safety requirements are being applied and they hire staff for the safety department. 2. Managers have been successful in motivating employees in using safety measures and ensuring organization’s safety with the help of incentive programs. Incentive programs also have a negative impact on the organization. Employees have manipulated incident reports and provided misleading information to managers to make sure that the manager continues using incentive programs. Due to manipulation and misleading data, managers have failed to counter safety issues at the right time. When managers stop incentive programs, employees return to their prior performance standards and in some cases standard of performance have even depleted. Maslow’s Hierarchy of need theory states that employees are motivated to fulfill their needs. Managers can motivate employees by helping employees fulfill these needs. The theory even states that individuals try to fulfill their basic needs first and then they pursue remaining needs. Managers can motivate employees to ensure that employees take care of the organization’s safety by providing them incentives which will help them purchase basic psychological needs such as food and shelter. An example of the safety needs is job security, if managers make employees feel that their jobs will not be taken away then employees will be motivated to ensure that their working environment is safe. Managers need to make the employees feel that they are a part of the organization; this will help in fulfilling employee’s belongingness need. Managers should provide work to the employees; this will fulfill employee’s self esteem needs. Once all the needs are fulfilled, emp loyees will start caring about the people around them and will make sure that their working environment is safe (Friend, 2010, 235). 4. McClelland stated that every individual is born with the need for power, affiliation